I’m told many people ignore the “Instructions” when reading Basic Instructions and just concentrate on the dialog. I understand that. I have referred to my cartooning-style as “the wall-of-text method.” I don’t recommend reading it that way, though. Often the instructions enhance the joke in the dialog.
I don’t know what Basic Instructions would have been like without the instructions part, or even if I could have done it. Often, I’d come up with one panel and the topic would give me a framework that led me to the other three jokes. Trying to come up with all four panels without the topic as a guide would have been much more difficult.